Up for multiple golden popcorn trophies, the "21 Jump Street" stud was joined by his lovely lady Jenna Dewan at the Gibson Amphitheatre venue.
As for his nominations, Channing is in the running for Best Cast along with Jonah Hill, Ice Cube, Dave Franco, Ellie Kemper and Brie Larson for their work in "21 Jump Street".
He's also competing for Best Fight for his rumble with Jonah Hill and Kid Gang and Best Kiss for his smooch with Rachel McAdams in "The Vow".
Sure to be quite the action-packed night, this year's MTV Movie Awards are being hosted by British funnyman Russell Brand while Emma Stone is to receive the first annual Trailblazer Award and Johnny Depp will be honored with the MTV Generation Award for over four decades worth of movie magic.
The show will also feature performances by The Black Keys, fun. and Wiz Khalifa while footage from the forthcoming films "The Dark Knight Rises" and "The Perks of Being a Wallflower" will be unveiled during the course of the ceremony.